Open until filled
Director of RNA & Formulations Core Facility at UBC
The deadline has been extended.
Job Description Summary
The RNA & Formulation Core Director is responsible for establishing and operating a new cost recovery core service facility which will provide RNA and formulations to academic and industrial users. Major responsibilities of the position include planning, preparing budgets and forecasting, providing technical expertise, implementing protocols, and managing research staff to deliver technical services. Key services of the core facility are to produce quality RNA and nanoparticle formulations for delivery to users, and it will be the responsibility of the Director to oversee operations of the facility.
Preference will be given to those with experience in producing RNA and nanoparticle formulations or an MSc/PhD in Molecular Biology or Biochemistry, and to an applicant with industrial (non-academic) laboratory experience including supervision of technicians or trainees. Extensive practical and theoretical knowledge on in vitro transcription of RNA, nanoparticle formulations, drug delivery and detailed knowledge of instrumentation required for production and quality control.
Open until filled
Graduate research projects
Noncoding RNA biology
Summary of responsibilities
The RNA and Noncoding Mechanisms of Disease Research Unit (www.sauvageaulab.org) is seeking to recruit a candidate wishing to pursue graduate studies (M.Sc. or PhD) in the field of noncoding RNAs and genome regulation. The group is located at the Montreal Clinical Research Institute (IRCM) and candidates can be affiliated to either University of Montréal or McGill University.
The Sauvageau lab combines genetically engineered animal models and human cellular systems with functional genomics and CRISPR-based genome editing techniques to perturb lncRNA functions and characterize their role at a cellular and physiological level. We also aim to understand the molecular grammar that underlies lncRNA function and uncover novel noncoding RNA-based mechanisms. For this, we use a combination of biochemistry, high-throughput and computational approaches to identify RNA-interacting macromolecules and RNA domains that mediate their function. Our goal is to better understand the impact that lncRNAs and noncoding regions have on development and reveal novel RNA-based mechanisms that could lead to the generation of novel diagnostics and therapies. The team is multi-disciplinary and part of a network of labs investigating RNA in genome regulation.
Strong academic record and pertinent experience in biochemistry, molecular and cellular biology, and/or in bioinformatics (an asset).
How to apply
Please send your resume, grades and a cover letter explaining why you want to join the lab. Also include the names and contact information for two referees to the Research Unit Director [email protected]